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Since its introduction in 1992, the SNL model of neuropathic pain has been widely used for various investigative works on neuropathic pain mechanisms as well as in screening tests for the development of new analgesic drugs. This model can be developed by tightly ligating the L5 and L6 segmental spinal nerves in the rat. Learn more: https://www.creative-biolabs.com/drug-discovery/therapeutics/spinal-nerve-ligation-snl-rat-model.htm